一、概述····················································································································································1二、基本内容·········································································································································2（一）基本原则····························································································································2（二）刺激性试验·······················································································································3（三）光毒性试验·······················································································································4（四）溶血性试验······················································································································5（五）结果分析及评价············································································································6（六）常见问题及处理············································································································7（七）不同剂型的中药、天然药物试验项目的选择············································9三、参考文献·······································································································································10四、附录··················································································································································11（一）刺激性试验方法·········································································································111、血管刺激性试验···············································································································112、肌肉刺激性试验···············································································································123、皮肤刺激性试验···············································································································124、粘膜刺激性试验···············································································································15（二）光毒性试验方法·········································································································20（三）溶血性试验方法·········································································································221、常规体外试管法（肉眼观察法）·········································································222、改进的体外溶血性试验法（分光光度法）·····················································243、体外红细胞计数法··········································································································254、体内溶血试验法（红细胞计数法）····································································25五、著者·················································································································································25